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  • 2008-2009

Pascal Imbeault

Selected Publications

• Drapeau S, Doucet É, Rabasa-Lhoret R, Brochu M, Prud’homme D and Imbeault P. Improvement in insulin sensitivity after weight loss does not affect hyperinsulinemia-induced reduction in total and high molecular weight adiponectin: a MONET study. Applied Physiology, Nutrition and Metabolism 36(2): 191-200, 2011.

• Imbeault P, Haman F, Blais JM, Pal S, Seabert T, Krümmel EM and Robidoux MA. Obesity and type 2 diabetes prevalence in adults from two remote First Nations communities in northwestern Ontario, Canada. Journal of Obesity, Article ID 267509, 2011.

• Elisha B, Karelis AD, Imbeault P and Rabasa-Lhoret R. Effect of acute hyperinsulinemia on total and high molecular weight adiponectin concentration in metabolically healthy but obese postmenopausal women: a Montreal Ottawa New Emerging Team (MONET) study. Diabetes and Metabolism 36(4): 319-321, 2010.

• Elisha B, Ziai S, Karelis AD, Rakel A, Coderre L, Imbeault P and Rabasa-Lhoret R. Similar associations of total adiponectin and high molecular weight adiponectin with cardio-metabolic risk factors in a population of overweight and obese postmenopausal women: a MONET study. Hormone and Metabolic Research 42(8): 590-594, 2010.

• Kasbia GS, Arneson JT and Imbeault P. No effect of oral administration of Momordica charantia Linn., on glycemia, energy expenditure and appetite: A pilot study in overweight men. Journal of Ethnopharmacology. 126 (1): 127-133, 2009.

Research Project:

White fat regulation of adipose tissue metabolism in humans (funded by the Natural Sciences and Engineering Research Council of Canada):
Apart from providing thermal and mechanical insulation, white adipose tissue is the central site of lipid storage in mammals. In addition to the central role of lipid storage, white adipose tissue has a major endocrine function secreting proteins in response to specific extracellular stimuli or changes in metabolic status. Using cellular (primary cell culture), biochemical (enzymes, metabolites) and molecular (RNA) techniques, we study the hormonal and nutritional influences governing the development and the secretory capacity of the adipocyte. At the moment, research in my laboratory can be grouped in two themes: 1) the role of fatty acids and carbohydrates on adipocyte metabolism; and 2) the effects of cold exposure on adipocyte’s secretory capacity.